Isiokwu na ụzọ:

• Ndị sonyere:Ngụkọta nke158 ndị nwoke na ụmụ nwanyị nwere ahụike na-eme agadi n'etiti20 na 59 afọe were ha n'ọrụ. Ndị ọrụ afọ ofufo nwere akụkọ ahụike siri ike ma ọ bụ nke na-adịghị ala ala, ndị riri ihe karịrị500 ml nke kọfị, tii, ihe ọṅụṅụ dị nro na ihe ọṅụṅụ na-aba n'anya kwa ụbọchị, ndị nana-aṅụ ihe ọṅụṅụ na-aba n'anya karịa ụbọchị abụọ n'izu, ndị na-ejikarị ihe mgbakwunye antioxidant eme ihe n'oge gara agaọnwa atọ, ndị na-ese siga, ndị nwere mgbatị ahụ siri ike, na ndị na-emezughị ụkpụrụ oriri kwa ụbọchị nke 500 - 2500 ml nke mmiri dị ọcha ka ewepụrụ. N'ikpeazụ, e kenyere ndị sonyere 41 tozuru oke na otu mmiri hydrogen (n = 22) na otu mmiri nkịtị (n = 19). Otú ọ dị, n'oge usoro ọmụmụ ihe, ndị sonyere 2 si na otu mmiri hydrogen na 1 si na mmiri nkịtị. N'ikpeazụ,20ndị sonyere na otu mmiri hydrogen na18n'ime otu mmiri nkịtị mezuru ule ntinye aka nke izu 4.
• Ụzọ ntinye aka:Otu mmiri hydrogen riri1.5 lita mmiri nke nwere hydrogen(ya na ntinye hydrogen nke 0.753 ± 0.012 mg / l) kwa ụbọchị, ebe otu mmiri nkịtị na-aṅụ ihe nha nha nke mmiri nkịtị. A chọrọ ka ndị sonyere mechaa mmiri na karama 500 ml n'ime otu awa ka emepechara ya. E wezụga kọfị, tii, ihe ọṅụṅụ dị nro, na ihe ọṅụṅụ na-aba n'anya, ọ dịghị mmiri ọzọ a kwadoro, a na-achịkwakwa ngụkọta nke ihe ọṅụṅụ ndị a na-aṅụ na-erughị 500 ml kwa ụbọchị.

• Ike Antioxidant na mmebi Oxidative: Mgbe izu anọ gachara, ma ịṅụ mmiri nkịtị na mmiri nwere hydrogen butere mmụba na serum biological antioxidant potential (BAP). N'ime ọnụ ọgụgụ ndị mmadụ n'ozuzu, ọ dịghị nnukwu ọdịiche dị n'etiti otu mmiri hydrogen na otu mmiri nkịtị n'ihe gbasara BAP. Otú ọ dị, maka ndị sonyere ihe karịrị afọ 30, ịṅụ mmiri hydrogen mere ka mmụba dị ukwuu na BAP (p = 0.028). N'ime ndị na-eto eto (<30 afọ), enweghi mmetụta dị ịrịba ama nke mmiri hydrogen na BAP (p = 0.534).
• Apoptosis nke Mkpụrụ ndụ Mononuclear Blood (PBMCs) na Profaịlụ nke Ọbara Ndị Mmadụ:Na mmalite, ọ dịghị nnukwu ọdịiche dị na ugboro ole mkpụrụ ndụ apoptotic n'ime ọbara n'etiti otu abụọ ahụ. Otú ọ dị, mgbe nyocha nke izu 4 gasịrị, ma e jiri ya tụnyere ìgwè mmiri nkịtị, ọnụ ọgụgụ nke PBMC apoptotic na otu mmiri hydrogen dị ntakịrị (p = 0.036). Ọzọkwa, site na nyocha cytometry eruba, a chọpụtara na ugboro ole mkpụrụ ndụ CD14+ na otu mmiri hydrogen belatara.
• Nyocha transcriptome:Nyocha usoro RNA nke PBMC gosiri na e nwere nnukwu ọdịiche dị n'etiti transcriptome nke otu mmiri hydrogen na nke otu mmiri nkịtị. Karịsịa, netwọk transcription nke metụtara nzaghachi mkpali na ụzọ akara NF-κB n'ime otu mmiri hydrogen na-agbadata nke ọma.